Healthspan Program KHARIS -
strategies for aging gracefully

KHARIS (grace in greek) is to develop new strategies that improve healthspan and lead to improved quality of life, as well as reducing healthcare spendings.

KHARIS is using systems and genetics approaches to understand the aging process. The research of Johan Auwerx spurred the development of new drugs, for the treatment of non-communicable diseases of the metabolic, cardio-vascular, renal and neuro-muscular system.

KHARIS' mission is to

• define personalised healthspan metrics and trajectories by integration of mouse and human data
• map predictive and causal factors of the decline of health, loss in resilience and age-related disease
• identify and validate candidate healthspan and disease targets
• develop modality agnostic strategies / therapeutics to increase healthspan and resilience
• create a digital twin of health to facilitate in silicon clinical trial